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What is Vicodin? This combination medication is used to relieve moderate to severe pain. It contains an opioid pain reliever (hydrocodone) and a non-opioid pain reliever (acetaminophen). Hydrocodone works in the brain to change how your body feels and responds to pain. Acetaminophen can also reduce a fever. 60 Pills $349.00 ADD TO CART 120 pills $449.00 ADD TO CART 180 Pills $559.00 ADD TO CART 240 Pills $649.00 ADD TO CART 300 Pills $749.00 ADD TO CART What is the strongest pain killer? Morphine. Morphine and morphine-like drugs (such as oxycodone, fentanyl and buprenorphine) are the strongest painkillers there are. Depending on your individual circumstances, these types of painkillers may be prescribed as a patch, an injection, or sometimes in a pump you control yourself. What is the difference between oxycodone and OxyContin? Oxycodone and OxyContin contain the same active ingredient: the prescription narcotic oxycodone. The differ...